《英文msh詞典》Multiple Exostoses,Hereditary
[入口詞] Multiple Exostoses,Hereditary
[主題詞] Exostoses,Multiple Hereditary
[英文釋義] Hereditary disorder transmitted by an autosomal dominant gene and characterized by multiple exostoses (multiple osteochondromas) near the ends of long bones. The genetic abnormality results in a defect in the osteoclastic activity at the metaphyseal ends of the bone during the remodeling process in childhood or early adolescence. The metaphyses develop benign,bony outgrowths often capped by cartilage. A small number undergo neoplastic transformation.